The news outlet cited the pope as saying his comments were not aimed at Trump.
"As it happens, it was looked at as if I was trying to debate the president, which is not in my interest at all," the pope reportedly said.
Fox News Digital has reached out to the White House for comment.
Trump last Sunday accused Pope Leo XIV of being "terrible" on foreign policy as the pontiff has criticized the U.S.-Israeli war on Iran.
"He talks about 'fear' of the Trump Administration, but doesn’t mention the FEAR that the Catholic Church, and all other Christian Organizations, had during COVID when they were arresting priests, ministers, and everybody else, for holding Church Services, even when going outside, and being ten and even twenty feet apart," Trump wrote in a Truth Social post.
"I don’t want a Pope who thinks it’s OK for Iran to have a Nuclear Weapon," he continued.
During a speech in Cameroon on Thursday, the pope said, "We must make a decisive change of course — a true conversion — that will lead us in the opposite direction, onto a sustainable path rich in human fraternity."
"The world is being ravaged by a handful of tyrants, yet it is held together by a multitude of supportive brothers and sisters!" he added.
"Woe to those who manipulate religion and the very name of God for their own military, economic or political gain, dragging that which is sacred into darkness and filth," the pope also said.
Fox News Digital’s Landon Mion contributed to this report.