Fox News Digital reached out to the White House on Thursday regarding the pontiff's comments in Cameroon.
But the president himself spoke about the pope on Thursday after he was asked about the religious figure's comments.
President Donald Trump said on Thursday that it is "very important that the Pope understands" that "Iran killed 42,000 people that were totally unarmed, they were protesters."
"Iran cannot have a nuclear weapon," the president asserted, saying that if the foreign nation did possess such a weapon, every nation in the world, including Italy, "would be in trouble."
"But the pope has to understand, Iran, very simple, Iran cannot have a nuclear weapon. The world would be in great danger," he declared.
Asked if he would meet with the pope to iron out their differences, Trump responded, "I don't think it's necessary."
Trump blasted the Catholic figure in a Truth Social post on Sunday night, declaring that the man "is WEAK on Crime, and terrible for Foreign Policy" and that he should "stop catering to the Radical Left, and focus on being a Great Pope, not a Politician."
"I don’t want a Pope who thinks it’s OK for Iran to have a Nuclear Weapon. I don’t want a Pope who thinks it’s terrible that America attacked Venezuela, a Country that was sending massive amounts of Drugs into the United States and, even worse, emptying their prisons, including murderers, drug dealers, and killers, into our Country," Trump declared in part of the lengthy post.
"And I don’t want a Pope who criticizes the President of the United States because I’m doing exactly what I was elected, IN A LANDSLIDE, to do, setting Record Low Numbers in Crime, and creating the Greatest Stock Market in History," he added.
In a Truth Social post on Tuesday, the president wrote, "Will someone please tell Pope Leo that Iran has killed at least 42,000 innocent, completely unarmed, protesters in the last two months, and that for Iran to have a Nuclear Bomb is absolutely unacceptable. Thank you for your attention to this matter. AMERICA IS BACK!!!"